Download ☆ Structurebased Ligand Design, Volume 6 By Klaus Gubernator – serv3.3pub.co.uk

Download ☆ Structurebased Ligand Design, Volume 6 By Klaus Gubernator – serv3.3pub.co.uk [Download] ➽ Structurebased Ligand Design, Volume 6 ➽ Klaus Gubernator – Serv3.3pub.co.uk Most drugs bind to a clearly defined macromolecular target that is complementary in terms of structure and chemistry This observation is the basic paradigm of structure based ligand design Although th Design, Volume PDF/EPUB » Most drugs bind to a clearly defined macromolecular target that is complementary in terms of Structurebased Ligand MOBI :ç structure and chemistry This observation is the basic paradigm of structure based ligand design Although this Ligand Design, Volume ePUB ´ method first emerged in the s it has already become a powerful tool for pharmaceutical research Much has been learned however since the first attempts to discover drugs on the basis of available biochemical and structural data Nowadays structure based ligand design is an established method for creating drugs with new structural features for modifying binding activities and pharmacokinetic properties and for elucidating binding modes and structure activity relationships This volume presents the underlying principles of the approach and highlights real life applications such as the discovery of HIV protease inhibitors It shows that structure based ligand design has many advantages over othertraditional approaches to designing new drugs providing it is employed properly and with a thorough knowledge of the pitfalls to avoid The straightforward presentation and extensive list of references to the original literature as well as numerous color figures illustrating structural relationships make this volume an indispensable tool for every scientist working in the area of drug discovery.

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